For 48 years since its founding, Echigo Yakuso has consistently researched and developed products that combine the power of natural wild plants and fermentation with a focus on health. Their flagship product, Echigo Yakuso Co., Ltd.'s Enzyme, combines three elements: wild plants as the "ingredients," ceramic jars as the "vessels," and Joetsu's climate, which is suitable for fermentation. It is the only product in the enzyme industry to have been recognized for its quality and safety by the medical organization Japan Association for the Prevention of Adult Diseases, and to be approved as a recommended product.